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| Name | Class |
|---|---|
| ORA, Inc. | INDUSTRY |
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Single-center, double-masked, randomized, placebo-controlled, parallel-group, efficacy and safety study using the Allergen BioCube (ABC).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Nasapaque Nasal Solution | Experimental | 250 ul in each nostril at Day 1 and Day 8 |
|
| Placebo Saline Nasal Solution | Active Comparator | 250 ul in each nostril at Day 1 and Day 8 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Nasapaque Nasal Solution | Drug |
| ||
| Placebo Saline Nasal Solution |
| Measure | Description | Time Frame |
|---|---|---|
| TNSS Total Nasal Symptom Score | Day 1 and Day 8 |
| Measure | Description | Time Frame |
|---|---|---|
| Nasal Inspiratory Flow | Day 1 and Day 8 | |
| Nasal Inflammation Score | Day 1 and Day 8 |
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Key Inclusion Criteria:
Key Exclusion Criteria:
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30881050 | Derived | Gomes PJ, Abelson MB, Stein L, Viirre E, Villafranca JE, Lasser EC. Iodixanol nasal solution reduces allergic rhinoconjunctivitis signs and symptoms in Allergen BioCube(R): a randomized clinical trial. J Asthma Allergy. 2019 Mar 1;12:71-81. doi: 10.2147/JAA.S150251. eCollection 2019. |
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| Drug |
|
| ID | Term |
|---|---|
| D006255 | Rhinitis, Allergic, Seasonal |
| ID | Term |
|---|---|
| D065631 | Rhinitis, Allergic |
| D012220 | Rhinitis |
| D009668 | Nose Diseases |
| D012140 | Respiratory Tract Diseases |
| D012130 | Respiratory Hypersensitivity |
| D010038 | Otorhinolaryngologic Diseases |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
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