Search for Biomarkers in Human Glaucoma: Lymphocytes Alterations and Rate of Progression

Search for Biomarkers in Human Glaucoma: Possible Correlations Between Alterations in Peripheral Lymphocytes and Disease Severity

The aim of this study was to evaluate the lymphocyte phenotype in primary open- angle glaucoma (POAG) patients compared to healthy subjects of the same age, in order to confirm the importance of immune responses in glaucoma and the possible correlation to the severity of the disease.

Inclusion Criteria:

• Clinical diagnosis of primary open-angle glaucoma
• age between 19 an 85 years old

Exclusion Criteria:

• age less than 19 or more than 85 yrs
• positive history for (a) neurodegenerative diseases, (b) autoimmune diseases, (c) cancer, (d) viral infection and (e) diabetes, (f)systemic inflammation