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Participants diagnosed with tibial femoral knee osteoarthritis will be assigned to one of three treatment groups including: active transcutaneous electrical nerve stimulation (TENS), placebo TENS, and a control group. Assignment of conditions will be concealed. All participants in each of the three groups will receive physical therapy for all 4 weeks of the intervention. Main outcome measures will include quadriceps central activation ratio, quadriceps torque production, WOMAC scores, visual analog pain scores during gait as well as knee joint kinetics and kinematics during gait. The purpose of this study is to to determine if the continuous use of TENS therapy for activities of daily living and rehabilitation will positively impact all outcome measures.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Active TENS | Experimental | Active TENS therapy for 4 weeks plus standard physical therapy for same time period. |
|
| Placebo TENS | Placebo Comparator | Placebo TENS for 4 weeks plus standard physical therapy for same time period. |
|
| Control Group | No Intervention | No TENS, standard physical therapy for 4 weeks. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Transcutaneous electrical nerve stimulation (TENS) | Device | Continuous TENS use |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Quadriceps central activation ratio | 2 and 4 weeks | |
| Quadriceps torque production | 2 and 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| WOMAC score | 2 and 4 weeks | |
| Visual analog pain score | 2 and 4 weeks | |
| Knee joint kinetics and kinematics |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Christopher Ingersoll, PhD | University of Virginia | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Virginia | Charlottesville | Virginia | 22908 | United States |
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| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| ID | Term |
|---|---|
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
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| ID | Term |
|---|---|
| D004561 | Transcutaneous Electric Nerve Stimulation |
| ID | Term |
|---|---|
| D004599 | Electric Stimulation Therapy |
| D013812 | Therapeutics |
| D026741 | Physical Therapy Modalities |
| D012046 | Rehabilitation |
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| Placebo TENS |
| Device |
Placebo TENS use |
|
| 2 and 4 weeks |
| D000698 |
| Analgesia |
| D000760 | Anesthesia and Analgesia |