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| Name | Class |
|---|---|
| University of Bologna | OTHER |
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The purpose of this study is to evaluate the antioxidant activity on skin photo induced damage of a food supplement and its anti-age properties.
To determine the antioxidant activity of the tested product the following clinical and instrumental evaluations will be performed:
To determine the anti-age properties of the tested product the following clinical and instrumental evaluations will be performed:
Moreover aim of the study is also to evaluate the best dosage of the beverage (1 or 2 servings of 250 ml/a day).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 1 Product 825 (2-servings day) | Experimental | 30 subjects drinking 2 servings day of Product 825 for 8 weeks |
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| Group 1 Product 824 (2 servings-day) | Experimental | 30 subjects drinking 2 servings-day of Product 824 for 8 weeks |
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| Group 2 Product 825 (1 serving-day) | Experimental | 30 subjects drinking 1 serving-day of Product 825 for 8 weeks |
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| Gruop 2 Product 824 (1 serving-day) | Experimental | 30 subjects drinking 1 serving-day of Product 824 for 8 weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Alixir - Pomegranate, apple and Açai drink / Placebo | Dietary Supplement | 250 ml/day Alixir/Placebo for Group 2 for 8 weeks 500 ml/day Alixir/Placebo for Group 1 for 8 weeks |
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| Measure | Description | Time Frame |
|---|---|---|
| Erythema evaluation (MED-optical densitometry) | T0 (basal conditions), T4 and T8 (after 4 and 8 week-treatment), T12 and T16 (follow-up visits - 12 and 16 weeks after T0) |
| Measure | Description | Time Frame |
|---|---|---|
| Skin evaluations (Skin texture - Hydration - Plastoelasticity - Epicutaneous pH) | T0 and T8 for skin evaluations - T0, T4, T8 and T12 for blood analysis | |
| Determination on blood samples of antioxidants diet components | T0 and T8 for skin evaluations - T0, T4, T8 and T12 for blood analysis |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Adele Sparavigna, Doctor | Derming SRL | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| DermIng S.r.l | Monza | MB | 20052 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Background | Elsner P., Berardesca E., Maibach H. Bioengineering of the skin: Water and the stratum corneum CRC Press, Boca Raton, 1994; Fuga GC, Spina C, Cavallotti C, Di Palma A, Lombardi G, Marmo W Computerized reflected optical densitometry. A research on the colour of the skin - Journal of Applied Cosmetology, 8:91-110,1990; Cosmetic, Toiletry and Fragrance Association of South Africa (CFTA), The European Cosmetic Toiletry and Perfumery Association (COLIPA), Japan Cosmetic Industry Association (JCIA) International sun protection factor (SPF) test method; October 2002; ICH Harmonised Tripartite Guideline - Guideline for Good Clinical Practice International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use: May 1996; Setaro M., Sparavigna A. Morphological Evaluation of Skin Surface by Fourier's Transform: A Study on the Phase and the Modulus |
| Label | URL |
|---|---|
| Sponsor | View source |
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| Haematological laboratory center | View source |