Levobupivacaine on Heart Rate Variability (HRV) in Spinal Anesthesia

Comparison of the Effects of Levobupivacaine and Bupivacaine on Heart Rate Variability in Spinal Anesthesia

The purpose of this study is to compare if the effect of levobupivacaine on autonomic nervous system smaller than that of bupivacaine.

Obtain the heart rate variability (in means and standard deviation, including the high frequency, low frequency and its ratio) data of before and after spinal anesthesia with ECG (and Heart Rate Variability Analyzer) in 2 groups. Meanwhile, record the blood pressure on each subject.

Inclusion Criteria:

• Indicated for spinal anesthesia

Exclusion Criteria:

• Allergic reaction to local anesthetics
• Coagulopathy
• Severe spinal deformity
• Cardiac diseases
• Metabolic diseases (such as DM, thyroid or adrenal diseases)