A Bioequivalence Study of 3 Formulations of Ondansetron in Healthy Adults (0869-095)(COMPLETED)

An Open-Label, Randomized, Single Dose, 3-period Crossover Study to Determine the Bioequivalence of 3 Formulations of Ondansetron in Healthy Young Adult Male and Female Subjects

This study will assess the bioequivalence of a Merck clinical trial formulation of ondansetron compared to a U.S. and non-U.S. marketed formulation of ondansetron.

Inclusion Criteria:

• If female, subject is not pregnant or breast-feeding
• Subject is a nonsmoker
• Subject is in good general health

Exclusion Criteria:

• Subject has a history of high blood pressure, asthma, or cardiovascular, liver, neurologic, or kidney disease
• Subject is taking prescription or nonprescription drugs that can not be discontinued during the study
• Subject is a habitual and heavy consumer of caffeine