A Study to Investigate Biomarkers of Skin Androgenization Following Testosterone Administration (0000-015)(COMPLETED).

A Pilot Study to Investigate Biomarkers of Skin Androgenization Following Short-Term Testosterone Administration in Healthy Postmenopausal Women

Postmenopausal women will receive testosterone gel or matching placebo gel daily. Sebum excretion rates will be measured before and after 6 weeks of treatment.

Inclusion Criteria:

• Subject is at least 3 years postmenopausal
• Subject is in good general health
• Subject is willing to avoid excess alcohol or strenuous physical activity during the study

Exclusion Criteria:

• Subject has donated a unit of blood or has taken an investigational drug in another clinical trial in the last 4 weeks
• Subject is a regular user of any illicit drugs
• Subject drinks excessive amounts of coffee, tea or cola
• Subject has used an estrogen or progestogens hormone replacement therapy in the past 6 months
• Subject has a history of cancer
• Subject has acne