Hemodynamic Changes in Off-pump Coronary Artery Bypass Grafting

Hemodynamic Changes in Off-pump Coronary Artery Bypass Grafting

The purpose of this study is to study the positioning and stabilization of different cardiac walls performed during off-pump coronary artery bypass grafting (CABG) may have dissimilar impact on hemodynamics.

The objective is to evaluate hemodynamics during distal coronary anastomoses in different cardiac walls.

• Twenty patients undergoing off-pump CABG monitored with pulmonary artery catheter and esophageal doppler will be enrolled.
• Patients with a left ventricular ejection fraction <50%, age >80 yr, creatinine >1.4 mg/dl, reoperation, valvular heart disease or chronic obstructive pulmonary disease were excluded
• Data will be collected after volemic and hemodynamic adjustments, after heart positioning and establishment of a suction stabilizer and before its removal in anterior, lateral or posterior wall artery anastomosis.
• Data was compared by means of two-way repeated measures ANOVA.

Inclusion Criteria:

• Normal left ventricular function
• Minimal to moderate surgical risk according to criteria proposed by Higgins et al. (JAMA. 1992 May 6;267(17):2344-8)

Exclusion Criteria:

• Patients with a left ventricular ejection fraction <50%,
• Age >80 yr
• Creatinine >1.4 mg/dl
• Reoperation
• Valvular heart disease
• Chronic obstructive pulmonary disease
• High surgical risk according to criteria proposed by Higgins et al. (JAMA. 1992 May 6;267(17):2344-8)