The Effects of Inhaled Nitric Oxide After Fontan Operation

The Effects of Inhaled Nitric Oxide on Patient Morbidity and Length of Hospital Stay Following Fontan Operation

Pleural effusions continue to be a post-operative complication seen after Fontan operation. This study will examine the use inhaled nitric oxide (iNO) given for 54 hours after Fontan operation to improve fluid balance. The study hypothesis is that inhaled nitric oxide after Fontan operation will improve fluid balance, thus decreasing the incidence of pleural effusions and shortening hospital stay.

Inclusion Criteria:

• Male/female patients
• Undergoing Fontan operation at the Nemours Cardiac Center at A. I. duPont Hospital for Children
• Written parental permission to participate in this research study

Exclusion Criteria:

• Any condition which the PI feels will interfere with the patient's safe and effective participation