Doxycycline and Ceftriaxone in Suspected Early Lyme Neuroborreliosis

Doxycycline and Ceftriaxone in Patients With Suspected Early Lyme Neuroborreliosis and Normal CSF Cell Count.

The investigators will compare doxycycline and ceftriaxone in treatment of patients with suspected early Lyme neuroborreliosis and normal CSF cell count. The study hypothesis is that the efficacy and adverse effects of both antibiotics are comparable.

Inclusion Criteria:

• age >15 years
• erythema migrans in 4 months period before neurologic symptoms
• normal CSF cell count
• absence of more defined clinical symptoms or signs for CNS involvement (radicular pain, meningeal signs, peripheral facial palsy).

Exclusion Criteria:

• pregnancy
• lactation
• allergy on doxycycline and ceftriaxone
• immune deficiency.