Subjective and Conjunctival Response to Edge Design of Different Silicone Hydrogels

Subjective and Conjunctival Response to Edge Design of Different Silicone Hydrogels

The purpose of this study was to evaluate the effect of different contact lens edge designs on the circumlimbal conjunctiva.

Inclusion Criteria:

• Minimum age of 18 years old
• Adapted contact lens wearer
• Sign informed consent
• Normal eyes with the exception of the need for visual correction
• Astigmatism less than or equal to -0.75 diopter
• Spherical prescription range between -10.00 and +6.00 diopters
• Other protocol-defined inclusion criteria may apply

Exclusion Criteria:

• Any known sensitivity to the test articles used in the study
• Monocular vision
• Lid or conjunctival infections or abnormalities
• Conjunctival staining greater than Grade 1
• Corneal staining greater than Grade 2
• Corneal edema or opacifications
• Aphakia
• Any previous corneal surgery
• Iritis
• Recent significant changes in visual acuity
• Ocular disease that contraindicates contact lens wear
• Tarsal abnormalities greater than Grade 2
• Any ophthalmic medication
• Any systemic medication or condition that might affect the subject's participation in the study
• Chronic upper respiratory infections or colds
• Pregnancy or planning to become pregnant
• Lactation
• Seasonal allergies
• Known infections or immunosuppressive disease
• Participation in other studies
• Other protocol-defined exclusion criteria may apply