Clinical Performance Comparison of Several Different Contact Lenses

Multicenter, Single-masked, Randomized, Parallel, Controlled Study to Compare Senofilcon A Contact Lenses to Currently Used Contact Lenses

The purpose of the study is to evaluate the possible benefits of second generation silicone hydrogel contact lenses.

Inclusion Criteria:

Subjects must:

• be existing soft contact lens wearers of the study control lenses
• require a distance visual correction in both eyes
• have a contact lens spherical distance requirement between -1.00 diopters (D) and -8.00D in both eyes
• have astigmatism less than or equal to 1.00D in both eyes
• be able to wear lenses available for this study
• be corrected to a visual acuity of 6/9 (20/30) or better in each eye
• have normal eyes with no evidence of abnormality or disease

Exclusion Criteria:

Subject are excluded for the following reasons:

• monovision corrected
• worn lenses extended wear in the last 3 months.
• require concurrent ocular medication
• grade 3 or 4 abnormalities
• grade 3 corneal staining in more than two regions
• anterior ocular surgery
• any other ocular surgery or injury within 8 weeks prior to study enrollment
• abnormal lachrymal secretions
• pre-existing ocular irritation that would preclude contact lens fitting
• corneal irregularities
• Polymethyl methacrylate (PMMA) or Rigid Gas Permeable (RGP) lens wear in past 12 weeks
• any systemic illness which would preclude contact lens wear
• diabetes
• infectious or immunosuppressive disease
• pregnancy or lactating, or planning pregnancy at time or enrollment
• participating in a concurrent clinical study or within last 60 days
• allergy to the standardized study care solution