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| ID | Type | Description | Link |
|---|---|---|---|
| 2008-004625-42 | EudraCT Number |
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PI left institution
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Study to assess the efficacy of intramyocardial bone marrow derived mononuclear cell therapy concerning left ventricular ejection fraction as measured by echocardiography.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Active Comparator | PCI plus BNNC Therapy after acute myocardial infarction |
|
| 2 | Active Comparator | Percutaneous Coronary Intervention after acute myocardial infarction |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Percutaneous Coronary Intervention | Procedure | common Percutaneous Coronary Intervention |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Assessment of the effect of a direct intramyocardial injection of bone marrow mononuclear cells (BMNC) on heart function (LVEF). | 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of th eexplanatory power of echocardiography, endocardial left ventricular electromechanical mapping (LVEMM) with NOGA and cardiac MRI as an endpoint for myocardial regeneration. | 12 months | |
| Collection of first evidence on the best type and time points for the determination of myocardial regeneration by NOGA and other parameters. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Karl-Heinz Kuck, MD, PhD | Asklepios Klinik St. Georg, Department of Cardiology | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Asklepios Klinik St. Georg | Hamburg | Germany |
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| ID | Term |
|---|---|
| D018487 | Ventricular Dysfunction, Left |
| ID | Term |
|---|---|
| D018754 | Ventricular Dysfunction |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D062645 | Percutaneous Coronary Intervention |
| ID | Term |
|---|---|
| D057510 | Endovascular Procedures |
| D014656 | Vascular Surgical Procedures |
| D013504 | Cardiovascular Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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| BMNC therapy |
| Procedure |
Injection of BMNC after common PCI |
|
| 12 months |
| D019060 | Minimally Invasive Surgical Procedures |