Bone Marrow Cells in Myocardial Infarction

Effects of Autologous Bone Marrow Celss on Acute ST-Elevation Myocardial Infarction

This study is aimed to assess the effect of bone marrow cells on arrhythmia risk variables in patients with a acute myocardial infarction.

This is a randomized, double-blinded study, where patients treated with thrombolytic therapy for acute myocardial infarction are randomized to receive bone-marrow derived stem cells or sham-infusion at the time percutaneous coronary intervention of the target vessel. The end-points are many arrhythmia risk variables, suchs as heart rate variability, T-wave alternans and many ECG variables as well as systolic and diastolic left ventricular function.

Inclusion Criteria:

• Acute ST-elevation myocardial infarction treated with thrombolytic therapy

Exclusion Criteria:

• Indication for rescue PCI, severe clinical heart failure, age <18 years