Study Evaluating The Effect Of A High-Fat Meal On The Pharmacokinetics Of Neratinib

An Open-Label, Randomized, Single-Dose, 2-Period Crossover Study To Determine The Effect Of A High-Fat Meal On The Relative Bioavailability And Pharmacokinetics Of A Single Dose Of The 240 mg Formulation Of Neratinib In Healthy Subjects

This study is being conducted to see if neratinib is absorbed, distributed, or eliminated differently when administered in the fasting state versus after a high-fat meal.

Inclusion Criteria:

• Healthy men and women of nonchildbearing potential, age 18 to 50 years.

Exclusion Criteria:

• Any previous or current clinically significant medical condition or disease.