Study Comparing 2 New Formulations of HKI-272 in Healthy Adult Subjects

A Single Dose Bioavailability Study of 2 New Formulations of HKI-272 (240 mg) Compared With a Reference Capsule and an Oral Solution in Healthy Adult Subjects

To evaluate the comparative bioavailability of 2 new tablet formulations of HKI-272 with a reference capsule and an oral solution in healthy subjects.

Criteria:

• Healthy male and female subjects aged 18 to 50 years.
• Women of nonchildbearing potential (WONCBP)