Evaluation of Predictive Proteic Profile on Mortality in the Acute Phase of Septic Shock in Cancer Patients

Evaluation of Predictive Proteic Profile on Mortality in the Acute Phase of Septic Shock in Cancer Patients

The mortality induced by infections in onco-hematological patients is abnormally high at the acute phase of septic shock. Consequently, it is important to detect the population with a high risk of short term mortality among patients with a septic shock. The aim of this study is the evaluation of predictive proteic profile on the short term mortality in the acute phase of septic shock in cancer patients.

Method: Monocentric prospective study with diagnostic and prognostic expectations.

Primary objective:

Identification and characterization of early proteic biomarkers predictive of short term mortality in cancer patients with septic shock.

Secondary objective:

Research of clinical and biological prognostic factors.

Inclusion Criteria:

• Patient from oncology or hematology with a septic shock
• Patient aged 18 years and older
• Inclusion within the 24 hours of the septic shock in the intensive care unit
• Signed consent according to the emergency reglementation

Exclusion Criteria:

• Pregnancy, breast feeding
• Patient with decision of care limitation
• Patient with legal protection