Pilot Study of Hippocampal Function in Type 1 Diabetes Mellitus (T1DM)

Pilot Study of Hippocampal Function in T1DM

This study is an expansion of a previous study done to determine how thinking skills relate to hypoglycemia (low blood sugar) and certain regions of the brain in children and adolescents. In this study, the investigators are testing thinking skills and measuring brain activity in adolescents with and without type 1 diabetes mellitus.

Inclusion Criteria:

• Age 13 - 18
• Right handed
• Diagnosis of Type 1 Diabetes OR normal sibling control
• If diabetic, then diagnosis for at least 2 years

Exclusion Criteria:

• Pregnant or lactating
• Chronic disease other than well-controlled asthma, or Hashimoto's thyroiditis.
• Other current serious medical illness
• Co-morbid psychiatric illness
• Co-morbid neurological illness
• Pre-maturity at birth
• Contraindication to MRI scan
• orthodontic braces.