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The purpose of this trial is to study the effects of different combinations of antiemetics on the incidence of late onset postoperative nausea and vomiting.
The authors will study the effect of many antiemetics on the occurrence of nausea and vomiting following strabismus surgery in pediatrics.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ondansetron-Dexa group | Active Comparator | Use 2 different antiemetics |
|
| Midazolam, Dexa group | Active Comparator | use of midazolam and dexamethasone |
|
| Placebo | Placebo Comparator | Saline will be given |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Placebo | Drug | Saline |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| Efficacy of antiemetics combination | 3 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Waleed Riad, MD, AB, SB | King Khaled Eye Specialist Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| king Khaled Eye Specialist hospital | Riyadh | 11462 | Saudi Arabia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 17437654 | Background | Riad W, Altaf R, Abdulla A, Oudan H. Effect of midazolam, dexamethasone and their combination on the prevention of nausea and vomiting following strabismus repair in children. Eur J Anaesthesiol. 2007 Aug;24(8):697-701. doi: 10.1017/S0265021507000166. Epub 2007 Apr 17. |
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| ID | Term |
|---|---|
| D020250 | Postoperative Nausea and Vomiting |
| D013285 | Strabismus |
| D014839 | Vomiting |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009325 | Nausea |
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| ID | Term |
|---|---|
| D012965 | Sodium Chloride |
| D017294 | Ondansetron |
| D003907 | Dexamethasone |
| D008874 | Midazolam |
| ID | Term |
|---|---|
| D002712 | Chlorides |
| D006851 | Hydrochloric Acid |
| D017606 | Chlorine Compounds |
| D007287 | Inorganic Chemicals |
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| Ondansetron, Dexamethasone |
| Drug |
Use of ondansetron and dexamethasone as combined antiemetics |
|
|
| Midazolam, dexamethasone | Drug | use of midazolam and dexamethasone as combined antiemetic |
|
|
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D015835 | Ocular Motility Disorders |
| D003389 | Cranial Nerve Diseases |
| D009422 | Nervous System Diseases |
| D005128 | Eye Diseases |
| D017670 |
| Sodium Compounds |
| D007093 | Imidazoles |
| D001393 | Azoles |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D002227 | Carbazoles |
| D007211 | Indoles |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D006575 | Heterocyclic Compounds, 3-Ring |
| D011246 | Pregnadienetriols |
| D011245 | Pregnadienes |
| D011278 | Pregnanes |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
| D013259 | Steroids, Fluorinated |
| D001569 | Benzodiazepines |
| D001552 | Benzazepines |