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Differences between BIS and Neurosense are important. This study can be terminated.
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The assessment of anesthesia depth was based, until recently, on the evolution of hemodynamic parameters. Nowadays it can be evaluated by several monitoring methods, derived from electroencephalogram analysis, namely the Bispectral Index (Aspect Medical Systems, Newton, USA). A new modality is currently under development: the NeuroSENSE (Cleveland Medical Devices Inc., Cleveland, OH 44103, USA). The goal of this study is to compare both monitoring modalities during anesthesia.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| patients receiving iv anesthesia |
| ||
| patients receiving balanced anesthesia |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| propofol, remifentanil, atracurium | Drug | propofol, remifentanil, atracurium dosages are adapted according to clinician's judgment |
|
| Measure | Description | Time Frame |
|---|---|---|
| Concordance between pairs of Bispectral Index and Neurosense indices during maintenance of anesthesia | Statistical analysis of concordance | at the end of each case |
| Measure | Description | Time Frame |
|---|---|---|
| Concordance between pairs of Bispectral Index and Neurosense indices during induction and emergence | Statistical analysis of concordance | at the end of each case |
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Inclusion Criteria:
Exclusion Criteria:
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Surgical patients
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| Name | Affiliation | Role |
|---|---|---|
| Marc Fischler, MD | Hôpital Foch | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Dept of Anesthesia, Hôpital Foch | Suresnes | 92150 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 16602568 | Background | Zikov T, Bibian S, Dumont GA, Huzmezan M, Ries CR. Quantifying cortical activity during general anesthesia using wavelet analysis. IEEE Trans Biomed Eng. 2006 Apr;53(4):617-32. doi: 10.1109/TBME.2006.870255. |
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| ID | Term |
|---|---|
| D015742 | Propofol |
| D000077208 | Remifentanil |
| D001279 | Atracurium |
| D000077149 | Sevoflurane |
| ID | Term |
|---|---|
| D010636 | Phenols |
| D001555 | Benzene Derivatives |
| D006841 | Hydrocarbons, Aromatic |
| D006844 | Hydrocarbons, Cyclic |
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| propofol, remifentanil, atracurium, sevoflurane | Drug | dosages are adapted according to clinician's judgment |
|
| EEG monitoring | Device | simultaneous monitoring with Bis and Neurosense |
|
| D006838 |
| Hydrocarbons |
| D009930 | Organic Chemicals |
| D011422 | Propionates |
| D000144 | Acids, Acyclic |
| D002264 | Carboxylic Acids |
| D010880 | Piperidines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D044182 | Benzylisoquinolines |
| D007546 | Isoquinolines |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D008738 | Methyl Ethers |
| D004987 | Ethers |
| D006845 | Hydrocarbons, Fluorinated |
| D006846 | Hydrocarbons, Halogenated |