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Funding withdrawn
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| Name | Class |
|---|---|
| Royal College of Surgeons, Ireland | OTHER |
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The purpose of this research is to determine the relationship between proteins and enzymes in the blood and how they work with platelets to form blood clots in patients with coronary artery disease. The investigators hypothesize that the relationship between these factors could potentially be useful in identifying patients at higher risk for heart attacks.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| coronary artery disease | Subjects with coronary artery disease undergoing percutaneous coronary intervention |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Blood draws | Other | Observational: blood draws only |
|
| Measure | Description | Time Frame |
|---|---|---|
| relationships between ADAMTS-13 activity, von Willebrand factor antigen and platelet-monocyte aggregates levels | Assess the relationships between ADAMTS-13 activity, von Willebrand factor antigen and platelet-monocyte aggregates levels in subjects with coronary artery disease prior to and after undergoing PCI in this exploratory study | change from baseline to after percutaneous coronary intervention |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with coronary artery disease undergoing percutaneous coronary intervention
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| Name | Affiliation | Role |
|---|---|---|
| Noel M. Caplice, M.D, Ph.D. | University College Cork, Ireland | Principal Investigator |
| Dermot Kenny, M.D. | Royal College Surgeons in Ireland | Study Director |
| David Foley, M.B. | Beaumont Hospital, Dublin, Ireland | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cork University Hospital | Cork | Ireland | ||||
| Beaumont Hospital |
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| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D001800 | Blood Specimen Collection |
| ID | Term |
|---|---|
| D013048 | Specimen Handling |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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serum, plasma
| Dublin |
| Ireland |
| D001161 |
| Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |
| D011677 | Punctures |
| D013514 | Surgical Procedures, Operative |
| D008919 | Investigative Techniques |