Determine the Effects of C-administration of AZD7325 and an Oral Contraceptive in Healthy Female Subjects

A Randomized, Open-Label, Two-way Crossover Study to Determine the Effects of Co-administration of AZD7325 and a Monophasic Oral Contraceptive Containing Ethinyl Estradiol and Norgestimate in Healthy Female Subjects

The purpose of this study is to evaluate the effect of repeated doses of AZD7325 on the pharmacokinetics of ORTHO-CYCLEN, a monophasic oral contraceptive

Inclusion Criteria:

• If previously pregnant, must be > 6 month post-partum at the time of randomization
• Body Mass Index (BMI) greater than or equal to 18 and less than or equal to 30 kg/m2

Exclusion Criteria:

• Use of any prescription medication within 14 days of screening
• current smoker or history of smoking within the last 3 months prior to enrollment
• Abnormal pap smear exam result within one year of enrollment.