A Children's Oncology Group Protocol for Collecting and Banking Pediatric Research Specimens Including Rare Pediatric Tumors
A Children's Oncology Group Protocol for Collecting and Banking Pediatric Research Specimens Including Rare Pediatric Tumors
This study is collecting and storing malignant, borderline malignant neoplasms, and related biological samples from young patients with cancer. Collecting and storing samples of tumor tissue, blood, and bone marrow from patients with cancer to study in the laboratory may help the study of cancer in the future.
OBJECTIVES:
I. Collect malignant, borderline malignant neoplasms, and related biological specimens from Children's Oncology Group institutions for cases in which there is no disease-specific biologic protocol.
II. Provide a repository for long-term storage of malignant, borderline malignant neoplasms, and related biological specimens from these patients.
III. Make specimens available to qualified researchers to understand the biology of cancer in these patients.
OUTLINE:
Tumor tissue samples, blood, and bone marrow aspirates are collected and stored for future analysis.
Inclusion Criteria:
Meets any of the following criteria:
Must have biological specimens including solid tumors and leukemias available
Solid tumors meeting the following criteria:
Snap frozen primary tumor OR OCT embedded primary tumor OR formalin fixed (block or tissue in formalin) primary tumor AND at least 10 unstained paraffin slides for NIH Mandated QC (tumors that have undergone central pathology review are allowed)
Pleural fluid or cytologic specimens meeting the following criteria:
At least 1 mL of fluid and at least 2 unstained cytospin slides (or 2 unstained smears)
ALL/AML
Not eligible for disease-specific biology or banking protocol
Denver, Colorado 80218, United States
Miami, Florida 33136, United States
Minneapolis, Minnesota 55404, United States
New Brunswick, New Jersey 08903, United States
New Hyde Park, New York 11040, United States
Houston, Texas 77030, United States
Spokane, Washington 99204, United States