This is a single-institution, prospective, one-to-one randomized controlled research study. Subjects medically determined to need a cholecystectomy will be consented for surgery and study participation prior to enrolment in this study. Patients will then be randomized to receive either a single port laparoscopic cholecystectomy or a four port laparoscopic cholecystectomy.

Inclusion Criteria:

• Pre-operative diagnosis of one of the following:

  • Pancreatic cholecystitis
  • Biliary cholic
  • Biliary dyskinesia
  • Choledocholithiasis status post endoscopic retrograde cholangiopancreatography/sphincterotomy
  • Gallbladder polyps
  • Other diagnosis at the discretion of the surgeon

Exclusion Criteria:

• Acute cholecystitis
• Gallstones > 2.5cm in length on ultrasound
• Suspected presence of common duct stones
• History of jaundice
• History of gallstone pancreatic