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The purpose of this study is to compare the efficacy for cervical ripening in labor induction between titrated and conventional oral misoprostol
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| conventional oral misoprostol | Active Comparator | misoprostol 50 micrograms oral every 4 hours until cervical dilatation 3 centimeters |
|
| titrated oral misoprostol | Experimental | misoprostol 20 micrograms oral every hour until cervical dilatation 3 centimeters |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| misoprostol | Drug | misoprostol 50 micrograms oral every 4 hours until cervical dilatation 3 cm |
|
| Measure | Description | Time Frame |
|---|---|---|
| success rate of cervical ripening in labor induction | 12 hours after intervention |
| Measure | Description | Time Frame |
|---|---|---|
| number of vaginal delivery | 24 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Kusol Russameecharoen, MD | Siriraj Hospital, Mahidol University Bangkok, Bangkok, Thailand | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Siriraj Hospital, Mahidol University | Bangkok | Bangkok | 10700 | Thailand |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21959071 | Derived | Thaisomboon A, Russameecharoen K, Wanitpongpan P, Phattanachindakun B, Changnoi A. Comparison of the efficacy and safety of titrated oral misoprostol and a conventional oral regimen for cervical ripening and labor induction. Int J Gynaecol Obstet. 2012 Jan;116(1):13-6. doi: 10.1016/j.ijgo.2011.07.027. Epub 2011 Sep 28. |
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| ID | Term |
|---|---|
| D016595 | Misoprostol |
| ID | Term |
|---|---|
| D011459 | Prostaglandins E, Synthetic |
| D011465 | Prostaglandins, Synthetic |
| D011453 | Prostaglandins |
| D015777 | Eicosanoids |
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| misoprostol | Drug | misoprostol 20 micrograms oral every hours until cervical dilatation 3 cm |
|
|
| D005231 |
| Fatty Acids, Unsaturated |
| D005227 | Fatty Acids |
| D008055 | Lipids |
| D012898 | Autacoids |
| D018836 | Inflammation Mediators |
| D001685 | Biological Factors |