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Pico-Salax is an osmotic and stimulant bowel cleansing agent used prior to colonoscopy. It is unknown whether splitting the doses (i.e. taking the second dose the morning of the colonoscopy) results in a better bowel cleansing, as research with other agents suggests this may be the case. This study aims to assess whether splitting the dose of Pico-Salax results in a better bowel cleansing than traditional dosing.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Split Dose | Experimental | Doses of Pico-Salax split: one dose administered the night prior to colonoscopy and the other dose administered the day of the procedure. |
|
| Traditional Dose | Active Comparator | Both doses of Pico-Salax taken the evening prior to colonoscopy. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pico-Salax | Drug | Both doses of Pico-Salax taken the evening prior to colonoscopy |
| |
| Measure | Description | Time Frame |
|---|---|---|
| bowel cleansing assessed by the Ottawa Bowel Preparation Scale | day of colonoscopy |
| Measure | Description | Time Frame |
|---|---|---|
| patient tolerance of preparation | day of colonoscopy |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lawrence Hookey, MD | Queen's University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hotel Dieu Hospital | Kingston | Ontario | K7L 5G2 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22192423 | Derived | Flemming JA, Vanner SJ, Hookey LC. Split-dose picosulfate, magnesium oxide, and citric acid solution markedly enhances colon cleansing before colonoscopy: a randomized, controlled trial. Gastrointest Endosc. 2012 Mar;75(3):537-44. doi: 10.1016/j.gie.2011.09.018. Epub 2011 Dec 21. |
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| ID | Term |
|---|---|
| C574900 | Pico-Salax |
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| Split Dose Pico-Salax |
| Drug |
One dose of Pico-Salax taken the evening prior to colonoscopy and the other the morning of the procedure. |
|