Influence of Protein Hydrolysis on Dietary Protein Digestibility and Metabolism in Healthy Subjects

Influence of Protein Hydrolysis on Dietary Protein Digestibility and Metabolism in Healthy Subjects

Hydrolysis of dietary protein may impact their gastrointestinal kinetics and further metabolism. The primary goal of this work was to measure the metabolic fate of intact or hydrolyzed protein using a protein of good nutritional quality, i.e., casein. A second aim of this study was to assess the true ileal digestibility of dietary protein using different methods including the hydrolyzed casein method and to measure its possible effect on endogenous intestinal N losses in humans.

Inclusion Criteria:

• healthy subjects
• BMI between 18 and 25

Exclusion Criteria:

• allergy to dairy proteins
• positive serology to AgHbS, HCV or HIV
• pregnancy
• abusive drug or alcohol consumption.