The investigators hypothesize that patients with Acute ST Elevation Myocardial Infarction may benefit from primary angioplasty with use of a drug eluting balloon/bare metal stent combination without impairing the process of normal vascular healing and endothelial function.

The goals of this study are:

1. To compare 6-month angiographic outcome after primary angioplasty using drug eluting balloon/bare metal stent combination versus drug eluting stent versus bare metal stent.
2. To compare stent apposition and stent endothelialization after primary angioplasty using drug eluting balloon/bare metal stent versus drug eluting stent versus bare metal stent.
3. To compare coronary endothelial function after primary angioplasty using drug eluting balloon/bare metal stent versus drug eluting stent versus bare metal stent.

Inclusion Criteria:

• STEMI within 12 hours of onset of complaints
• Candidate for primary PCI with stent-implantation
• Successful thrombus aspiration defined by no angiographic signs of thrombus a the site of plaque rupture and TIMI flow more or equal 1

Exclusion Criteria:

• Unable to give written informed consent
• Diabetes and Type C- coronary lesion
• Previous PCI or CABG of infarct related vessel
• Left main stenosis more than 50%.
• Triple vessel disease with stenosis more than 50% in 3 epicardial coronary arteries
• Target vessel reference diameter less than 2.5 and more than 4.0 mm
• Target lesion length more than 25 mm
• Intolerance for aspirin or clopidogrel
• Life expectancy less than 12 months
• Women with child bearing potential