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There are two principal ways of draining the remnant of the pancreas back into the intestine after removal of the head of the pancreas for cancer. This can be performed either to the jejunum or to the stomach. The aim of this study is to randomly allocate consenting patients to one of the two arms to study whether the leak rates from the anastomosis and the outcomes after the surgery are affected.
Previous papers have shown similar results in both groups although non randomized data suggested that the Pancreaticogastrostomy (drainage into the stomach) may be superior
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Active Comparator | Pancreaticojejunostomy for reconstruction after pancreaticoduodenectomy |
|
| 2 | Active Comparator | Pancreaticogastrostomy for reconstruction after pancreaticoduodenectomy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| type of anastomosis after pancreaticoduodenectomy | Procedure | pancreaticojejunostomy (arm 1) versus pancreaticogastrostomy (arm 2)for reconstruction of the pancreatic remnant after pancreaticoduodenectomy |
| Measure | Description | Time Frame |
|---|---|---|
| pancreatic fistula rate | 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| mortality | 90 days | |
| Hospital stay | 90 days | |
| need for postoperative intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Hariharan Ramesh, MS MCh | Lakeshore Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Lakeshore Hospital & Research Center | Kochi | Kerala | 682024 | India |
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| ID | Term |
|---|---|
| D010190 | Pancreatic Neoplasms |
| D010185 | Pancreatic Fistula |
| ID | Term |
|---|---|
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004701 | Endocrine Gland Neoplasms |
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| 90 days |
| major complication | 90 days |
| D004066 |
| Digestive System Diseases |
| D010182 | Pancreatic Diseases |
| D004700 | Endocrine System Diseases |
| D016154 | Digestive System Fistula |
| D005402 | Fistula |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |