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The purpose of this study is to determine whether exercise is beneficial for people with rheumatoid arthritis(RA) taking antiTNFalpha medication
Substantial progress has been made in the medical management of RA over the past decade but at present no drug therapy leads to long-term remission for all patients with RA. People may still continue to experience physical, psychological and functional consequences which could benefit from rehabilitation.little research exists on the effects of exercise for people with RA taking anti-TNFalpha therapy medication.
It is proposed to conduct a randomized controlled trial to examine the effects of group exercise therapy in a gym setting or in a hydrotherapy pool compared to a control group.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Experimental | Gym group exercise intervention |
|
| 2 | Experimental | Hydrotherapy group exercise intervention |
|
| 3 | No Intervention | Control group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Gym exercise group intervention | Other | Gym based circuit class |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| Stanford Health Assessment Questionnaire | Baseline, 8 weeks and 24 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| 50 foot Walk Test | Baseline, 8 weeks and 24 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Oliver FitzGerald, MB, BcH, BAO | University College Dublin | Principal Investigator |
| Tara Cusack, PhD, MMedSc, | University College Dublin | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Our Lady's Hospice | Dublin | Dublin | 6W | Ireland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21232112 | Derived | Reid A, Brady A, Blake C, Mongey AB, Veale DJ, FitzGerald O, Cusack T. Randomised controlled trial examining the effect of exercise in people with rheumatoid arthritis taking anti-TNFalpha therapy medication. BMC Musculoskelet Disord. 2011 Jan 13;12:11. doi: 10.1186/1471-2474-12-11. |
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| ID | Term |
|---|---|
| D001172 | Arthritis, Rheumatoid |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
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| ID | Term |
|---|---|
| D035061 | Control Groups |
| ID | Term |
|---|---|
| D015340 | Epidemiologic Research Design |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D012107 | Research Design |
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| Hydrotherapy group exercise intervention | Other | Hydrotherapy group exercise class |
|
|
| Control group | Other | No intervention |
|
| D003240 |
| Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| D001519 | Behavior |
| D008722 | Methods |