Smoking Reduction or Cessation With Nicotine Replacement Therapy

Smoking Reduction or Cessation With Nicotine Replacement Therapy. A Placebo Controlled Double Blind Trial With Nicotine Gum or Inhaler.

The purpose of this study is to test the success rate of smoking reduction or cessation with different nicotine products.

To test if smoking reduction or cessation is induced with different nicotine products and to investigate the possible health benefits of smoking reduction

Inclusion Criteria:

• Age above 18
• Smoking >/= 15 cigarettes/day
• Having smoked for 3 years or more
• CO >/= 10ppm at inclusion
• Want to reduce smoking
• Prepared to adhere to the protocol
• Willing to provide signed informed consent
• Having made at least one serious attempt to quit smoking

Exclusion Criteria:

• Unstable angina pectoris, myocardial infarction within the last three months
• Use of other nicotine-containing products such as cigars, pipes, snuff
• Current use of NRT or involved in behavioral or pharmacological smoking cessation/reduction program
• Pregnancy/lactation or intended pregnancy
• Under psychiatric care or medication that might interfere with the trial
• Abuse of alcohol or any other drug