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The Scottish National and District swimming teams will be screened for asthma and rhinitis using both mannitol challenge and sport-based exercise challenge.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Scottish swimming team |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| no intervention | Other | this is a screening study, not an interventional study |
|
| Measure | Description | Time Frame |
|---|---|---|
| Tidal Nitric Oxide | This test will be performed prior to entering the pool, and on exiting the pool |
| Measure | Description | Time Frame |
|---|---|---|
| Mannitol Challenge | This test will be performed once on a district and once on a national squad training day | |
| Sport-based Challenge | This test will be performed once on a district and once on a national squad training day |
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Inclusion Criteria:
Exclusion Criteria:
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The Scottish national and district swimming teams
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| Name | Affiliation | Role |
|---|---|---|
| Karine L Clearie, MBBS, MRCP | Asthma and Allergy Research Group | Principal Investigator |
| Brian J Lipworth, MBchB | Asthma and Allergy Research Group | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The national swimming academy in Stirling | Stirling | Stirlingshire | FK9 4LA | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20214665 | Result | Clearie KL, Williamson PA, Vaidyanathan S, Short P, Goudie A, Burns P, Hopkinson P, Meldrum K, Howaniec L, Lipworth BJ. Disconnect between standardized field-based testing and mannitol challenge in Scottish elite swimmers. Clin Exp Allergy. 2010 May;40(5):731-7. doi: 10.1111/j.1365-2222.2010.03461.x. Epub 2010 Mar 1. |
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All members of the squad were offered the opportunity to take part.
The scottish national and district teams were assessed during training weekends.
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| ID | Title | Description |
|---|---|---|
| FG000 | Scottish Swimming Team |
| Title | Milestones | Reasons Not Completed | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
|
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| ID | Title | Description |
|---|---|---|
| BG000 | Scottish Swimming Team |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Categorical | Count of Participants |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Secondary | Mannitol Challenge | Not Posted | This test will be performed once on a district and once on a national squad training day | Participants | ||||||||||||
| Secondary | Sport-based Challenge | Not Posted | This test will be performed once on a district and once on a national squad training day | Participants |
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| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Scottish Swimming Team |
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| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Dr Karine Clearie | University of Dundee | 01382 496440 | k.clearie@dundee.ac.uk |
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| ID | Term |
|---|---|
| D001249 | Asthma |
| D012220 | Rhinitis |
| ID | Term |
|---|---|
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
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| Nasal Nitric Oxide | This test will be performed prior to entering the pool, and on exiting the pool |
| Skin Prick Test | This test will be performed once on a district and once on a national squad training day |
| Mini Nasal Lavage | This test will be performed prior to entering the pool, and on exiting the pool |
| Participants |
|
| Age, Continuous | Mean | Standard Deviation | years |
|
| Sex: Female, Male | Count of Participants | Participants |
|
| Region of Enrollment | Number | participants |
|
| Primary | Tidal Nitric Oxide | Data from all participants was analysed | Posted | Geometric Mean | 95% Confidence Interval | ppb | This test will be performed prior to entering the pool, and on exiting the pool |
|
|
|
| Secondary | Nasal Nitric Oxide | Not Posted | This test will be performed prior to entering the pool, and on exiting the pool | Participants |
| Secondary | Skin Prick Test | Not Posted | This test will be performed once on a district and once on a national squad training day | Participants |
| Secondary | Mini Nasal Lavage | Not Posted | This test will be performed prior to entering the pool, and on exiting the pool | Participants |
| 0 |
| 0 |
| 0 |
| 0 |
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| D012130 |
| Respiratory Hypersensitivity |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D009668 | Nose Diseases |
| D010038 | Otorhinolaryngologic Diseases |