The Physiological Consequence of Silicone-hydrogel Care-solution Bio-incompatibility

The Physiological Consequence of Silicone-hydrogel Care-solution Bio-incompatibility

The purpose of this study is to more objectively evaluate potential lens-material/care solution bio-incompatibilities. We will do this by measuring corneal staining and the amount of fluorescein dye diffusion into the eye.

Inclusion Criteria:

• At least 18 years of age.
• Best correctable vision to 20/40 in each eye.
• Possess a functional spectacle prescription to allow adequate vision during the de-adaptation and fluorometry measurement period.
• No known ocular or systemic allergies, which may interfere with contact lens wear.
• No known systemic disease, or need for medication that may interfere with contact les wear (i.e. antihistamines, beta-blockers, steroids, ect.).

Exclusion Criteria:

• Subjects demonstrating any medical condition that may affect the results of this study SHOULD NOT be enrolled. The following are specific conditions that exclude subjects from enrollment in this study.
• Eye (ocular) or systemic allergies that may interfere with contact lens wear.
• Clinically significant corneal swelling (greater than 3 or 4 on a 0-4 scale), corneal blood vessel growth (vascularization), corneal staining, bulbar redness, tarsal redness, or any other abnormality of the cornea that may cause unsafe contact lens wear.
• Are taking part in any other study or have taken part in a study within the last 14 days.
• Are pregnant, or anticipating to become pregnant during the course of the study.