Effect of Dietary Fiber on Glucose & Lipids in Non Insulin Dependent Diabetes Mellitus (NIDDM)

Effect of Dietary Fiber on Glucose, Lipid, and Mineral Metabolism in Patients With Non Insulin Dependent Diabetes Mellitus

Effect of Dietary Fiber on glucose, lipid, and mineral metabolism in patients with non insulin dependent diabetes mellitus.

Two diets will be compared,a low fiber diet and a high fiber diet. These two diets will differ only in the content of total dietray fiber derived from natural food products. The diets will be identical in terms of total energy, percentage of total energy as proteins, fat and carbohydrates.

Inclusion Criteria:

• NIDDM
• age 35 to 80 years
• stable oral hypoglycemic treatment for at least one month
• fasting triglycerides < 500 mg/dl

Exclusion Criteria:

• insulin dependent NIDDM
• insulin dependent diabetes
• hepatic disease
• significant hepatic dysfunction
• signifiacnt renal dysfunction
• presence of significant hematological, neurological, cardiovascular or gastrointestinal disorder, unless stable for past 6 months,
• serious intercurrent illness or anticipated major surgery
• female pregnant or likely to become pregnant
• chronic drug abuse, alcoholism or psychaitric disorder within the past 2 years
• treated with beta adrenergic blockers
• on lipid lowering drugs