The Influence of Remote Ischemic Preconditioning on Acute Kidney Injury After Cardiac Surgery

The Influence of Remote Ischemic Preconditioning on Acute Kidney Injury After Cardiac Surgery

Acute kidney injury is associated with cardiopulmonary bypass during heart surgery and its pathogenesis is similar to that of ischemia-reperfusion injury. Remote ischemic preconditioning attenuates myocardial ischemia-reperfusion injury in patients undergoing coronary bypass surgery. The investigators hypothesize that such preconditioning reduces the incidence of acute kidney injury associated with cardiopulmonary bypass.

Inclusion Criteria:

• Patient undergoing heart surgery on cardiopulmonary bypass.

Exclusion Criteria:

• Known peripheral vascular disease of the lower extremities associated with active skin necrosis or infection.
• End-stage renal disease.
• Inability to give informed consent.