Interest of Flow Cytometry for the Diagnosis, the Follow up and Specific Immunotherapy (SIT) Arrest of Hymenoptera Venom Allergy

Interest of Flow Cytometry for the Diagnosis, the Follow up and SIT Arrest of Hymenoptera Venom Allergy

The aim of this study is to show that flow cytometry can be an accurate tool to help physicians regarding the diagnosis, the SIT decision and the SIT arrest of hymenoptera venom allergy.

75 patients having a story of reaction to hymenoptera venom will be selected for this trial.

Blood samples will be analyzed at: inclusion visit, Week 1 visit, Week 3 visit, Week 10 and Week 21 visit.

Inclusion Criteria:

• Adult patient (18 - 70 years)
• Patient being informed and accepting to participate in the study with signature of informed consent
• Patients having a clinical systematic and local, loco-regional story of reaction to the piqures of hymenopterans.
• Patients treated by SIT for at least 5 years
• Patients benefiting from a national insurance health

Exclusion Criteria:

• Children
• Pregnant woman or who breast-feed
• Patient under antihistaminic or corticoid for less than 8 days before the blood drawing
• Protected Patient
• Patient not having given his agreement after it was informed