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The aim of this study is to assess the current management strategies in a pan-European "real-life" setting to uncover the unmet need in this area: non-variceal gastrointestinal bleedings.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Patients admitted to the hospital, or inpatients admitted for another reason, presenting with overt non-variceal upper GI bleed manifesting as hematemesis/coffee ground vomiting, melena, hematochezia, as well as other clinical or laboratory evidence of acute blood loss from the upper gastrointestinal tract |
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| Measure | Description | Time Frame |
|---|---|---|
| To describe clinical outcomes associated with current strategies of endoscopic and pharmacological treatment in several European countries, in respect of bleeding continuation, rebleeding, surgery and in-hospital mortality | Up to 30 days after the episode (bleeding) |
| Measure | Description | Time Frame |
|---|---|---|
| To describe clinical management and how this compares across countries and Hospital types | Up to 30 days after the episode (bleeding) | |
| To assess predictive factors for clinical management strategies and predictive factors related to clinical outcomes |
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Inclusion Criteria:
Exclusion Criteria:
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Patients admitted to the hospital, or inpatients admitted for another reason, presenting with overt non-variceal upper GI bleed manifesting as hematemesis/coffee ground vomiting, melena, hematochezia, as well as other clinical or laboratory evidence of acute blood loss from the upper gastrointestinal tract
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| Name | Affiliation | Role |
|---|---|---|
| Ángel Lanas, MD | Hospital Clínico Universitario Lozano Blesa, Zaragoza (Spain) | Principal Investigator |
| Javier N Rivero, MSc | Medical Department, AstraZeneca Spain | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Research site | Aalst | Belgium | ||||
| Research site |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23225523 | Derived | Lanas A, Aabakken L, Fonseca J, Mungan Z, Papatheodoridis G, Piessevaux H, Rotondano G, Nuevo J, Tafalla M. Variability in the management of nonvariceal upper gastrointestinal bleeding in Europe: an observational study. Adv Ther. 2012 Dec;29(12):1026-36. doi: 10.1007/s12325-012-0069-x. Epub 2012 Dec 6. | |
| 23161291 | Derived |
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| Up to 30 days after the episode (bleeding) |
| To assess health care resource consumption in patients admitted with non-variceal upper gastrointestinal bleeding and the main drivers | Up to 30 days after the episode (bleeding) |
| Anderlecht |
| Belgium |
| Research site | Assebroek | Belgium |
| Research site | Braine-l'Alleud | Belgium |
| Research site | Brasschaat | Belgium |
| Research site | Bruges | Belgium |
| Research site | Brussels | Belgium |
| Research site | Charleroi | Belgium |
| Research site | Deurne | Belgium |
| Research site | Edegem | Belgium |
| Research site | Geraardsbergen | Belgium |
| Research site | Ghent | Belgium |
| Research site | Hasselt | Belgium |
| Research site | Herentals | Belgium |
| Research site | Kortrijk | Belgium |
| Research site | Lier | Belgium |
| Research site | Liège | Belgium |
| Research site | Mechelen | Belgium |
| Research site | Ottignies Lln | Belgium |
| Research site | Tielt | Belgium |
| Research site | Tournai | Belgium |
| Research site | Turnhout | Belgium |
| Research site | Wetteren | Belgium |
| Research site | Wilrijk | Belgium |
| Research site | Zottegem | Belgium |
| Research site | Athens | Greece |
| Research site | Larissa | Greece |
| Research site | Thessaloniki | Greece |
| Research site | Bolzano | Italy |
| Research site | Cosenza | Italy |
| Research site | Crema | Italy |
| Research site | Forlì | Italy |
| Research site | Milan | Italy |
| Research site | Naples | Italy |
| Research site | Novara | Italy |
| Research site | Revenna | Italy |
| Research site | Roma | Italy |
| Research site | S. Giovanni Rotondo | Italy |
| Research site | Siena | Italy |
| Research site | Trieste | Italy |
| Research site | Arendel | Norway |
| Research site | Ålesund | Norway |
| Research site | Bodø | Norway |
| Research site | Drammen | Norway |
| Research site | Fredrikstad | Norway |
| Research site | Kristiansand | Norway |
| Research site | Levanger | Norway |
| Research site | Lillehammer | Norway |
| Research site | Oslo | Norway |
| Research site | Rud | Norway |
| Research site | Stavanger | Norway |
| Research site | Tromsø | Norway |
| Research site | Trondheim | Norway |
| Research site | Tønsberg | Norway |
| Research site | Almada | Portugal |
| Research site | Angra do Heroísmo | Portugal |
| Research site | Braga | Portugal |
| Research site | Caldas da Rainha | Portugal |
| Research site | Castelo Branco | Portugal |
| Research site | Covilha | Portugal |
| Research site | Funchal | Portugal |
| Research site | Leiria | Portugal |
| Research site | Ponta Delgada | Portugal |
| Research site | Santarém | Portugal |
| Research site | Torres Novas | Portugal |
| Research site | Alcázar de San Juan | Spain |
| Research site | Alicante | Spain |
| Research site | Barcelona | Spain |
| Research site | Burgos | Spain |
| Research site | Córdoba | Spain |
| Research site | Huesca | Spain |
| Research site | La Cuesta de Arguijon | Spain |
| Research site | Las Palmas de Gran Canaria | Spain |
| Research site | Logroño | Spain |
| Research site | Madrid | Spain |
| Research site | Marbella | Spain |
| Research site | Murcia | Spain |
| Research site | Ourense | Spain |
| Research site | Oviedo | Spain |
| Research site | Pamplona | Spain |
| Research site | Sabadell | Spain |
| Research site | Santiago de Compostela | Spain |
| Research site | Seville | Spain |
| Research site | Valencia | Spain |
| Research site | Zaragoza | Spain |
| Research site | Ankara | Turkey (Türkiye) |
| Research site | Antalya | Turkey (Türkiye) |
| Research site | Batman | Turkey (Türkiye) |
| Research site | Bursa | Turkey (Türkiye) |
| Research site | Diyarbakır | Turkey (Türkiye) |
| Research site | Elâzığ | Turkey (Türkiye) |
| Research site | Gaziantep | Turkey (Türkiye) |
| Research site | Istanbul | Turkey (Türkiye) |
| Research site | Izmir | Turkey (Türkiye) |
| Research site | Konya | Turkey (Türkiye) |
| Research site | Malatya | Turkey (Türkiye) |
| Research site | Mersin | Turkey (Türkiye) |
| Mungan Z. An observational European study on clinical outcomes associated with current management strategies for non-variceal upper gastrointestinal bleeding (ENERGIB-Turkey). Turk J Gastroenterol. 2012;23(5):463-77. doi: 10.4318/tjg.2012.0402. |
| 21480935 | Derived | Lanas A, Aabakken L, Fonseca J, Mungan ZA, Papatheodoridis GV, Piessevaux H, Cipolletta L, Nuevo J, Tafalla M. Clinical predictors of poor outcomes among patients with nonvariceal upper gastrointestinal bleeding in Europe. Aliment Pharmacol Ther. 2011 Jun;33(11):1225-33. doi: 10.1111/j.1365-2036.2011.04651.x. Epub 2011 Apr 11. |
| ID | Term |
|---|---|
| D006471 | Gastrointestinal Hemorrhage |
| D006470 | Hemorrhage |
| D014456 | Ulcer |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D010437 | Peptic Ulcer |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D004378 | Duodenal Diseases |
| D007410 | Intestinal Diseases |
| D013272 | Stomach Diseases |
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