Use of Closed-loop Anesthesia in Pediatric Patients

Target-Controlled Infusion of Propofol and Remifentanil During General Anaesthesia Guided by the Index Bispectral: Comparison in Pediatric Patients Between Manual Perfusion and Automated Perfusion

To compare manual administration of propofol and remifentanil and dual closed-loop using bispectral index as the control variable during pediatric anesthesia

Inclusion Criteria:

• class ASA I, II or III
• general anesthesia scheduled to last more than one hour
• intraoperative hemorrhage planned to be less than 15% of the blood volume

Exclusion Criteria:

• Combined general and regional anesthesia,
• Patients with a pacemaker or scheduled for a cardiac or brain surgical procedure,
• History of a neurological or a psychiatric disorder, or central brain lesion,
• Patients receiving a psychotropic treatment or a a morphine agonist-antagonist,
• Allergy to latex, propofol, remifentanil, morphine, muscle relaxant, or to a component,
• Hypersensibility to remifentanil or to a derivate of fentanyl,
• Scheduled postoperative ventilation or sedation.