A Study Of The Effect Of PF-04802540 On Sleep Measures

Subject- And Investigator-Blinded, Sponsor-Open, Randomized, Single-Dose, Placebo-Controlled, 3-Way Crossover Study To Study Effects Of PF-04802540 On Polysomnography Endpoints In Healthy Volunteers

The purpose of this study is to determine if PF-04802540 decreases REM sleep.

Inclusion Criteria:

• Healthy male and/or female (nonchildbearing potential) subjects between the ages of 18 and 55 years, inclusive
• Body Mass Index (BMI) between 18 to 32 kg/m2, inclusive, and a total body weight >45 kg (99 lbs)
• Non-users of nicotine

Exclusion Criteria:

• Evidence or history of clinically significant medical illness
• A history of seizures, including childhood febrile seizures
• Any condition possibly affecting drug absorption