Effect of Moisturizing Creams on Skin Barrier Function

ClinicalTrials.gov ID

NCT00771121

Lead Sponsor

ACO Hud Nordic ABINDUSTRY

Overall Status

Unknown status

Study Type

Interventional

Phase

Phase 4

Last Update Posted

Oct 13, 2008Estimated

Brief Summary

This study is a randomized, double-blind, placebo-controlled bilateral study on the effect of moisturizing creams on skin barrier function. The hypothesis is that a new active emulsion has a better influence on skin barrier function comapred to its placebo.

• Atopic Eczema

• urea/lactic acid
• Placebo

Ages Eligible for Study

Adult (18-64)Older Adult (65+)

Sexes Eligible for Study

All

Accepts Healthy Volunteers

No

Eligibility Criteria

Inclusion Criteria:

• Dry skin barrier disorders such as atopic dermatitis or Malassezia eradicated head and neck dermatitis.
• Rough or clinically normal skin on the volar aspect of the forearm.
• Either gender
• Age between 18 and 65 years
• Written Informed Consent

Exclusion Criteria:

• Possible allergy to ingredients in the study medications.
• Use of any concomitant medication that may interfere with the study related activities or assessment of efficacy.
• Any patient related factor suggesting potential poor compliance with study procedures (e.g. psychiatric disorders, history of alcohol or substance abuse).
• Any serious medical condition which, in the opinion of the investigator, may interfere with the evaluation of the results.
• Pregnancy or breast feeding, or patients who plan to become pregnant during the course of the study.

Lead Sponsor

ACO Hud Nordic ABINDUSTRY

lena.holm.ab@telia.com0706-382722

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