This study is a randomized, double-blind, placebo-controlled bilateral study on the effect of moisturizing creams on skin barrier function. The hypothesis is that a new active emulsion has a better influence on skin barrier function comapred to its placebo.

Inclusion Criteria:

• Dry skin barrier disorders such as atopic dermatitis or Malassezia eradicated head and neck dermatitis.
• Rough or clinically normal skin on the volar aspect of the forearm.
• Either gender
• Age between 18 and 65 years
• Written Informed Consent

Exclusion Criteria:

• Possible allergy to ingredients in the study medications.
• Use of any concomitant medication that may interfere with the study related activities or assessment of efficacy.
• Any patient related factor suggesting potential poor compliance with study procedures (e.g. psychiatric disorders, history of alcohol or substance abuse).
• Any serious medical condition which, in the opinion of the investigator, may interfere with the evaluation of the results.
• Pregnancy or breast feeding, or patients who plan to become pregnant during the course of the study.