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Atrial Fibrillation (AF) is one of the most common postoperative complications after coronary artery bypass grafting (CABG). Postoperative AF produces a substantial impact on hospital resources with an estimated annual expenditure of over $1 billion. This includes the cost of pharmacological treatment and the cost of the increased length of stay. The incidence of AF is about 30-40% in CABG patients and increases with age of the patient. As the average age of the patient that undergoes CABG surgery is increasing, it is critical to find a way to prevent or reduce the incidence of this complication.
We propose a prospective, randomized, controlled study to determine the role of pulmonary vein isolation by bipolar ablation in the prevention or reduction of postoperative AF. The block- randomization plan will be used to maintain balance of the study and control arms throughout the study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pulmonary Vein isolation | Experimental | Patients in this arm will receive pulmonary vein isolation during surgery |
|
| Standard of care | No Intervention | Subjects in this arm will receive standard of care and no pulmonary vein isolation |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Isolation of pulmonary veins with Bipolar radiofrequency ablation | Procedure |
|
| Measure | Description | Time Frame |
|---|---|---|
| Reduced incidence of Postoperative Atrial fibrillation | 12 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15102 | United States |
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