Study Evaluating The Tolerability Of Multiple Doses Of HKI-272

A Blinded, Randomized, Multiple-Dose, Parallel Group Study to Characterize the Occurrence of Mild to Moderate Diarrhea After Administration of Neratinib Either 240-mg Once Daily or 120-mg Twice Daily for 14 Days to Healthy Subjects

Study to investigate the occurence of diarrhea after either once daily or twice daily dosing for 14 days.

Inclusion Criteria:

• Healthy male and female (non-child bearing potential) subjects
• Ages 18-50.