To determine the effects of WelChol tablets on serum lipids, lipoproteins, apolipoproteins, and lipoprotein particle size in patients who were stabilized on atorvastatin therapy for at least 4 weeks.

Inclusion Criteria:

• Male or female > or greater than 18 years of age
• On a stable dose of atorvastatin
• LDL-C > or = to 115 mg/dL and < or = to 250 mg/dL
• TG < or = to 300 mg/dL
• Women are not pregnant or breast-feeding or planning to become pregnant
• Women of child-bearing potential had a hysterectomy or tubal-ligation, or
• women were post menopausal, or
• women practiced an acceptable method of contraception as specified in the protocol

Exclusion Criteria:

• BMI > 40 kg/m2
• History of allergic or toxic reaction to colesevelam HCl
• History of swallowing disorders
• Any serious disorder that could impact the conduct of the study
• History of drug or alcohol abuse