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The purpose of this study is to determine the efficacy of three different interventions to improve treatment adherence among patients with arterial hypertension or diabetes in rural Cameroon.
Non communicable chronic diseases such as arterial hypertension (AH) and diabetes (DM) are a great burden for public health in Cameroon. However, outside the main cities access to appropriate diagnosis and treatment of these health-conditions is still very poor.
The Swiss NGO "Fondation Coopération Afrique" started in 2007 a program to integrate chronic disease management with focus on AH and DM into the primary health care system of peripheral non-physician health facilities in a rural area of Central Cameroon. A first evaluation after one year revealed very low treatment adherence among the newly diagnosed patients as the main challenge.
In order to improve patient's adherence we expose them randomly to one of three interventions:
The first intervention consists in a written agreement on long-lasting therapy (treatment contract). Patients get information about the importance of a regular long term treatment and personal engagement to follow treatment and clinical controls regularly.
The second intervention introduces in addition to the treatment contract a reminder system. In case of follow-up failure a community worker traces the patient to recall the visit at the health centre.
The third intervention consists of the treatment contract combined with a financial incentive in form of one month free treatment after four months of regular follow-up.
We allocated randomly one of the three interventions to each health center.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Active Comparator |
| |
| 2 | Active Comparator |
| |
| 3 | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Treatment contract | Other | Patients signs in for a agreement - to respect a regular follow-up at the health facility. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of patients with regular follow-up one year after the treatment was started | One patient year |
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of missed control-visits | One patient year | |
| Treatment response of diabetic patients (fasting blood glucose) | One patient year | |
| Treatment response of patients with arterial hypertension (blood pressure) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Engelbert Manga, MD, MPH | Medical district officer of Mfou, Ministry of public health of Cameroon | Study Director |
| Niklaus D Labhardt, MD | Representant of the foundation Coopération Afrique, Switzerland | Principal Investigator |
| Beat Stoll, MD, MPH | Institute of social and preventive medicine, University of Geneva, Switzerland | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Medical districts of Mfou, Mbankomo Obala and Esse in Central Cameroon | Divisions of Mefou and Lékié | Central Province | 4056 | Cameroon |
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| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D006973 | Hypertension |
| D000073296 | Noncommunicable Diseases |
| D010349 | Patient Compliance |
| D000074822 | Treatment Adherence and Compliance |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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| Tracing and recall at home by a community worker | Other | The local health committee sends out a member to trace the patient and to motivate him to take up again regular treatment visits. |
|
| Incentive | Other | Incentive by giving free treatment after a 4-month regular follow-up |
|
| One patient year |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010342 | Patient Acceptance of Health Care |
| D015438 | Health Behavior |
| D001519 | Behavior |