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To define a rational pharmacological management of pain for the subjects under opioid maintenance therapy (methadone or buprenorphine), it is first of all necessary to estimate the efficiency of the current practices on pain management as well as their potentially noxious consequences, in particular on the long term opioid maintenance therapy.
The objective of the study is to compare the efficiency of the opioid maintenance therapy according to the arisen of an acute painful phenomenon requiring an analgesic management for these patients. At first, this work will allow to determine the results on acute pain of the current practices for these patients. The comparison of the long term consequences on opioid maintenance therapy between the patients that presented an acute painful phenomenon and the control patients should help to improve acute pain management for these patients while limiting the risk of relapse in the abused consumption of psychoactive substances.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group P | Exposed to an acute painful phenomenon requiring an analgesic management | ||
| Group C | Control, not exposed to acute pain |
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| Measure | Description | Time Frame |
|---|---|---|
| Retention rate under buprenorphine or methadone treatment defined as the percentage of patients still under treatment during the follow-up | 1, 3, 6 and 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| pain, anxiety, drugs, alcohol and other substances abuse and dependence, drug prescription (included for pain treatment and opioid maintenance) | 1, 3, 6 and 12 months |
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Inclusion Criteria:
Exclusion Criteria:
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Patients under opioid maintenance therapy
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| Name | Affiliation | Role |
|---|---|---|
| Maryse Lapeyre-Mestre, MD | University Hospital, Toulouse | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital Toulouse | Toulouse | 31059 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24284855 | Result | Bounes V, Palmaro A, Lapeyre-Mestre M, Roussin A. Long-term consequences of acute pain for patients under methadone or buprenorphine maintenance treatment. Pain Physician. 2013 Nov-Dec;16(6):E739-47. |
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| ID | Term |
|---|---|
| D059787 | Acute Pain |
| ID | Term |
|---|---|
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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