Pitavastatin on Carotid Intima-media Thickness

Pitavastatin Evaluation of Atherosclerosis Regression by Intensive Cholesterol-Lowering Therapy

This study is aimed to analyze the effects of aggressive and conventional lipid lowering therapy with Pravastatin on carotid intima-media thickness (IMT) in patients with hyperlipidemia and abnormal thickening of IMT.

Inclusion Criteria:

• Diagnosed as having hyperlipidemia
• LDL-C at the time of enrollment is no less than 100
• Common carotid IMT is 1.1 mm and over

Exclusion Criteria:

• Received or planned to receive intervention on carotid arteries during the study period
• Overt liver dysfunction (ALT; 100 IU/L and over)
• Overt renal dysfunction (serum creatinine; 2.0 mg/dL and over)
• Receiving Cyclosporin
• Hyperreactive to Pitavastatin
• During pregnancy or lactation