Mometasone and Markers of Airway Inflammation

The Effects of Mometasone on Markers of Airway Inflammation

A post-marketing study to look at the effects of Asmanex on markers of airway inflammation.

Patients with asthma and not treated with anti-inflammatory medications were studied. This was a parallel, randomized, placebo-controlled study to investigate the effects of Asmanex on markers of airway inflammation including exhaled nitric oxide, airway reactivity, FEV1 and nitrates/nitrites and pH in exhaled breath condensate.

Inclusion Criteria:

• Asthma
• non-smoker
• FEV1 of at least 60% predicted

Exclusion Criteria:

• Pregnancy or lactation
• Corticosteroid use in past 30 days