To evaluate symptomatic outcome and HRQoL in GERD patients treated following a new CP Guideline.

Inclusion Criteria:

• Signed informed consent
• Age above 18
• Subjects with typical GERD symptoms: predominant heartburn/regurgitation
• Naive patients or off PPI treatment in the last 2 months

Exclusion Criteria:

• Inability to read and understand PRO instructions
• Patient not suitable to be treated following the AEG guidelines
• Concomitant treatment with NSAID, antiplatelet drugs
• Previous PPI failure

Patients with typical GERD symptoms consulting in specialized care setting and are managed following the new local GERD guidelines