This a non-interventional multi-centre study to evaluate the symptom load and management strategies in PPI-treated GERD patients with persistent GERD symptoms..

Inclusion Criteria:

• Provision of informed consent
• Subjects with a diagnosis of GERD and with predominant typical GERD symptoms: heartburn/regurgitation
• Subjects who fail to obtain satisfactory symptomatic response after their first full course (4-8 weeks) of standard dose PPI (once a day)

Exclusion Criteria:

• Inability to read and/or understand Patient Reported Outcomes questionnaires
• Subjects where the only reason for the visit is renewing the prescription
• A history of an incomplete response to PPI treatment prior to current course of treatment

PPI-treated patients consulting with persistent GERD symptoms in Primary Care. The patients must have a diagnosis of GERD with predominant typical GERD symptoms and fail to obtain satisfactory symptomatic response after the first full course of standard dose PPI. The patients must have been on continuous PPI treatment with unchanged doses according to local labelling during the last 4-8 weeks prior to the enrolment visit.