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The purpose of the study is to map regions of brain activation following rectal stimulation in children with irritable bowel syndrome (IBS) and healthy controls.
Our first aim is to compare the brain areas activated rectal stimulation in boys and girls with IBS and healthy children. Our second aim is to compare the anatomic regions of the brain activated during rectal stimulation in pre and post-pubertal male and female subjects between 10-18 yrs of age.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| IBS | Children between the ages of 10 and 18 who meet Rome III criteria for IBS as determined by a pediatric gastroenterologist. | ||
| Control | Healthy children between the ages of 10 and 18. |
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| Measure | Description | Time Frame |
|---|---|---|
| We intend to measure the degree of brain activation following rectal stimulation | 4 years |
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Inclusion Criteria:
Exclusion Criteria:
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Children will be selected from the Gastroenterology Clinic at Children's Hospital of Wisconsin.
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| Name | Affiliation | Role |
|---|---|---|
| Manu Sood, MD | Medical College of Wisconsin | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
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| 1889716 | Background |
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| ID | Term |
|---|---|
| D043183 | Irritable Bowel Syndrome |
| ID | Term |
|---|---|
| D003109 | Colonic Diseases, Functional |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D005767 | Gastrointestinal Diseases |
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| D004066 | Digestive System Diseases |